Hemin Binding to DNA with Bis-Dentate Acridine Intercalator.
نویسندگان
چکیده
منابع مشابه
Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA.
Bis-acridine orange peptides carrying two acridine oranges at the epsilon-amino moieties of both terminal lysines of a tetra(lysine) chain showed a ca. 200-fold fluorescence enhancement upon addition of double stranded DNA.
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Methods for the synthesis of N1, N8-bis(9-acridinyl)-N4-(4-hydroxybenzyl)spermidine and N1, N7-(hydroxybenzyl)-bis-(3-aminopropyl)amine were investigated. Thus monocyanoethylation of 4-methoxybenzylamine followed by treatment with 4chlorobutyronitrile gave the dinitrile N-(2-cyanoethyl)-N-(3-cyanopropyl)-4-methoxybenzylamine. Subsequent in situ reduction with lithium aluminium hydride gave the ...
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In the title complex, [PtBr(2)(C(13)H(9)N)(2)], the Pt(II) ion is four-coordinated in a slightly distorted square-planar environment by two N atoms from two acridine ligands and two Br atoms. The Pt atom is located on an inversion centre, and thus the asymmetric unit contains one half of the complex and the PtN(2)Br(2) unit is exactly planar. The dihedral angle between the PtN(2)Br(2) unit and ...
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Thermodynamic studies on the interactions between intercalator-neomycin conjugates and a DNA polynucleotide triplex [poly(dA).2poly(dT)] were conducted. To draw a complete picture of such interactions, naphthalene diimide-neomycin (3) and anthraquinone-neomycin (4) conjugates were synthesized and used together with two other analogues, previously synthesized pyrene-neomycin (1) and BQQ-neomycin...
متن کاملtrans-Bis(acridine-κN)dichloridopalladium(II)
In the title complex, [PdCl(2)(C(13)H(9)N)(2)], the Pd(II) ion is four-coordinated in an essentially square-planar environment by two N atoms from two acridine ligands and two Cl(-) anions. The Pd atom is located on an inversion centre, and thus the asymmetric unit contains one half of the complex and the PdN(2)Cl(2) unit is exactly planar. The dihedral angle between the PdN(2)Cl(2) unit and th...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1994
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.42.988